青云英语翻译

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TNBBCs有一个具体的区别于其他乳腺肿瘤,如他们的表达谱Ki - 67抗原,波形蛋白,层粘连蛋白和p53的表达增强,而Bcl - 2表达低于其他亚型(2007年,罗德里格斯皮尼利亚等。Han等人2008)。一些研究发现,肿瘤抑制基因的表达PTEN的更频繁地在TNBBC失去比非TNBC(Perren等1999;萨尔等2008; Hu等人2009年)。 PTEN基因在磷脂酰肌醇3激酶途径,这是关键的是在许多乳腺癌亚型的作用。有趣的是,如果这个途径在乳腺癌的影响,无论是表达PTEN或PIK3CA丢失,表明一个基因的活性损失可能失去其他(萨尔等人,2005)的选择性压力减轻。与PTEN表达缺失是三重
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